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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK18
All Species:
5.76
Human Site:
S178
Identified Species:
14.07
UniProt:
Q7Z418
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z418
NP_862823.1
384
43671
S178
F
F
T
R
P
L
L
S
K
W
C
P
K
S
L
Chimpanzee
Pan troglodytes
XP_521614
383
43558
S178
F
F
T
R
P
L
L
S
K
W
C
P
K
S
L
Rhesus Macaque
Macaca mulatta
XP_001095493
383
43605
K178
F
F
T
R
P
L
S
K
W
C
P
K
S
L
F
Dog
Lupus familis
XP_544037
381
43021
E177
L
F
P
P
H
L
R
E
W
C
C
R
L
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q6VV64
394
44385
K189
C
L
P
H
D
I
F
K
W
R
S
L
P
L
C
Rat
Rattus norvegicus
Q6Q1P3
405
45333
K200
C
L
P
R
D
I
S
K
W
R
P
L
L
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513320
339
38516
F141
F
R
K
L
W
S
R
F
P
C
T
K
R
R
Q
Chicken
Gallus gallus
XP_001234729
358
41274
F155
S
K
I
L
A
S
K
F
C
P
G
S
T
C
I
Frog
Xenopus laevis
Q63ZI0
374
42700
S155
G
M
H
S
T
D
V
S
M
E
N
M
V
T
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001022681
372
42061
P161
L
Y
A
I
I
G
I
P
L
M
L
L
F
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.4
73.9
N.A.
64.9
65.1
N.A.
44.5
41.6
20.5
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
100
97.9
98.4
82.8
N.A.
76.9
76.5
N.A.
58.5
55.7
36.9
N.A.
N.A.
N.A.
N.A.
48.1
N.A.
P-Site Identity:
100
100
40
20
N.A.
0
6.6
N.A.
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
40
20
N.A.
6.6
13.3
N.A.
13.3
6.6
26.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
20
0
0
0
0
0
0
0
10
30
30
0
0
10
30
% C
% Asp:
0
0
0
0
20
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% E
% Phe:
40
40
0
0
0
0
10
20
0
0
0
0
10
0
10
% F
% Gly:
10
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
10
20
10
0
0
0
0
0
0
0
10
% I
% Lys:
0
10
10
0
0
0
10
30
20
0
0
20
20
0
0
% K
% Leu:
20
20
0
20
0
40
20
0
10
0
10
30
20
50
20
% L
% Met:
0
10
0
0
0
0
0
0
10
10
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
30
10
30
0
0
10
10
10
20
20
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
40
0
0
20
0
0
20
0
10
10
10
0
% R
% Ser:
10
0
0
10
0
20
20
30
0
0
10
10
10
20
0
% S
% Thr:
0
0
30
0
10
0
0
0
0
0
10
0
10
10
10
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
10
0
0
0
40
20
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _